After the performance last week, I'm not sure why we'd want to change too much. Asiata obviously comes back in, but given McIntosh was only signed on Tuesday, not sure it's wise to bring him into a spine position, and move Moylan (which will also weaken the defensive line).
If McIntosh had been playing full back regularly in the last couple of years there might be more of a case for it, but he's been playing on the wing. If he does come in, we'll have to play slightly differently because he won't do the job O'Brien or Moylan have done at full back. We've seen Hardaker trying to play like an extra half, and it never went well.