Quote wrencat1873="wrencat1873"It's going to be an "interesting" few months and it would be more interesting to know just how many people who have had 0ne or two doses of the vaccine are still contracting covid.
I realise this may have a negative effect on the vaccine program and that it's probably more important to ensure that the take up of the vaccine is as high as possible but, there are plenty of double jabbed people contracting the virus and whilst I will happily bow to your knowledge on vaccines, what would be the effect of any new variant(s), especially when we have a significant increase in overseas travel on the way.'"
It's called Vaccine Breakthrough, PHE are doing the study and they will use our technology platform to do a lot of it. I work with them, I can't discuss details but they are planning comprehensive work. If it is reassuring at all vaccine breakthrough to do with the individuals response to the vaccine rather than variants. They will also do reinfection studies.
We (my company) have made around 60 variants of covid, including several strains of the delta and the C37 etc. We use a standard sample in all our tests that's calibrated to the WHO reference material, it's a pool of several covid positive convalescent individuals, it's from early last year so the infection was wild type (Wuhan strain). All the variants we test show massive antibody binding from that sample and ACE2 inhibition - direct inhibition of ACE2 binding to the viral protein. What that means is that all the variants so far (as I said we have made around 60), are still identified and strongly bound by antibodies from Wuhan strain infected individuals.
I want to be reassuring because we are in a really good place with the vaccines, they are highly effective against all forms of the virus so far and the people at the sharp end of this are all pretty confident that no mutation will appear that completely sidesteps the massive immune response the vaccines generate. I'm not being political, just factual. Booster shots are looking highly effective as well.